The PlA1/PlA2 polymorphism lies in the gene for your βthree (GPIIIa) subunit of αIIbβthree (GPIIb-IIIa). This integrin serves to be a receptor for adhesive proteins fibrinogen and von Willebrand factor and is also important with the cohesive Qualities of platelets. Recognition of such proteins as soluble ligands requires αIIbβthree t… Read More